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Synergies
By Thomas F. Varley
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A newsletter about the hunt for understanding and insight in the face of complexity.
Experimental History
By Adam Mastroianni
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1) Find what's true and make it useful. 2) Publish every other Tuesday. 3) Photo cred: my dad.
Optimally Irrational
By Lionel Page
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Deciphering why people and society work the way they do
Personal Science
By Richard Sprague
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Science for personal, not professional use. Published every Thursday.
Secretorum
By Roger’s Bacon
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happy the dumb beast, wretched the mortal
The personal Substack of our head editor, Roger's Bacon
- The Seeds of Science Newsletter
Trevor Klee’s Newsletter
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Long, niche posts, mostly about biology
Preserving Hope
By Ariel Zeleznikow-Johnston
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Tracking progress in turning fate into choice through brain preservation. Official newsletter of the Brain Preservation Foundation.
Vectors of Mind
By Andrew Cutler
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Machine Learning Psychometrics / Snake Cult
Samstack
By Sam Atis
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A newsletter about social science, the future, and why people behave in the way that they do.
MOD 171
By Mod 171
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How do minds work, and how do you teach them things? Actually, what are minds?
Polypharmacy
By Nils Wendel
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Rationalist-adjacent musings on things we do in psychiatry
King Canute
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I like to write in a variety of fields to spread my mistakes more thinly.
Conspicuous Cognition
By Dan Williams
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Writer. Academic philosopher. Writing about philosophy, psychology, evolution, politics, artificial intelligence, and more.
Amateur Gods
By Josie Zayner
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Stories and thoughts from the cutting edge of genetic biohacking
Mechanics of Aesthetics
By Åsmund Folkestad
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A theoretical physicist’s contemplations on Beauty in a world of computation.
Hopeful Monsters
By Étienne
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Culture, technology, and other macromutations
Bio Stuff
By Eryney Marrogi
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Mostly about biology, medicine and machine learning, sometimes about other stuff.
Explorations.ph 🧭
By Kahlil Corazo @ Explorations.ph
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Ongoing season: essays towards my next book, Rajah Versus Conquistador: Operating Among Psychopaths and Psychic Megafauna
Auraist. The best writers on Substack.
By Sean
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Trusted by 70K+ readers, we pick the best-written books from US and UK new releases and prize shortlists, and publish articles by world-class authors on prose style and AI writing. Plus the satire The Demon Inside David Lynch.
THE EGG AND THE ROCK
By Julian Gough
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Novelist Julian Gough (author of Minecraft's End Poem) redescribes the universe.
interpoiesis
By the seeker
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Bits of Wonder
By Kasra
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deepdives into science, philosophy, and how to be a human
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